Grief

One day of grief is an hundred years, as Cardan observes: 'Tis carnificina hominum, angor animi, as well saith Aretaeus, a plague of the soul, the cramp and convulsion of the soul, an epitome of hell; and if there be a hell upon earth, it is to be found in a melancholy man's heart.

Robert Burton, The Anatomy of Melancholy, Part. I, Sect. 4, Memb. I (Prognosticks of Melancholy)